68 Results for "

Dioscorea cayenensis Lam.

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "Dioscorea cayenensis Lam." in MCE Product Catalog:

44
44 Publications Verification
Art. -Nr.: HY-14644
CAS. Nr.: 541550-19-0
Reinheit:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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44
44 Publications Verification
Art. -Nr.: HY-14644A
CAS. Nr.: 870087-36-8
Reinheit:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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1
1 Cited Publications
Art. -Nr.: HY-N2283
CAS. Nr.: 55659-75-1
Deltonin, a steroidal saponin, isolated from Dioscorea zingiberensis, has antitumor activity; Deltonin inhibits ERK1/2 and AKT activation.
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1
1 Cited Publications
Art. -Nr.: HY-N0429
CAS. Nr.: 20086-06-0
Diosbulbin B, a diterpene lactone, is an anticancer agent. Diosbulbin B is an orally active component of Dioscorea. bulbifera L. Diosbulbin B can inhibit cell proliferation, induce G0/G1 phase arrest and apoptosis. Diosbulbin B can induce autophagy and mitochondrial dysfunction. Diosbulbin B can induce liver injury. Diosbulbin B can be used for the research of cancer, such as non-small cell lung cancer (NSCLC) .
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Art. -Nr.: HY-129467
CAS. Nr.: 56472-29-8
Reinheit:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
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Art. -Nr.: HY-150229
CAS. Nr.: 2803699-70-7
Reinheit:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
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Art. -Nr.: HY-N4271
CAS. Nr.: 54848-30-5
Protogracillin is a steroidal furostanol saponin. Protogracillin can be isolated from the rhizomes and tubers of Dioscorea zingiberensis C.H. Wright. Protogracillin is hydrolyzable to Prosapogenin A (HY-N6940). Protogracillin exhibits antithrombotic activity. Protogracillin can be used in research related to cardiovascular diseases .
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Art. -Nr.: HY-N8503
CAS. Nr.: 147821-49-6
Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
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Art. -Nr.: HY-N8760
CAS. Nr.: 60347-67-3
Batatasin IV is an LTA4H inhibitor with anti-inflammatory activity. Batatasin IV is also a natural product that can be obtained from Dioscorea batatus. Batatasin IV can be used in research in the area of inflammation .
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Art. -Nr.: HY-N10842
CAS. Nr.: 88140-31-2
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
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Art. -Nr.: HY-N3765
CAS. Nr.: 66756-57-8
Target:  

Apoptosis

Forschungsgebiete:  

Metabolic Disease

Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells .
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Art. -Nr.: HY-N10803
CAS. Nr.: 15575-50-5
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
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Art. -Nr.: HY-164915
CAS. Nr.: 1218932-97-8
Target:  

Bacterial

Forschungsgebiete:  

Metabolic Disease

5-InoAz is an inositol analogue containing an azide group, which is used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
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Art. -Nr.: HY-N9097
CAS. Nr.: 122001-32-5
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
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Art. -Nr.: HY-N0080
CAS. Nr.: 28095-18-3
Synonyms: Peucedanol methyl ether
Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .
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Art. -Nr.: HY-N0940
CAS. Nr.: 51415-00-0
Batatasin I is a natural product that can be isolated from tuberous roots of Dioscorea batatas, with antifungal activity and anti-inflammatory effects .
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Art. -Nr.: HY-N7047
CAS. Nr.: 91095-48-6
8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice .
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Art. -Nr.: HY-14644B
CAS. Nr.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Forschungsgebiete:  

Infection Inflammation/Immunology

Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
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Art. -Nr.: HY-N12066
CAS. Nr.: 1459260-68-4
Progenin III palmitate is a steroid glycoside ester isolated from Dioscorea cayenensis rhizomes .
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Art. -Nr.: HY-N11919
CAS. Nr.: 1810733-76-6
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM) .
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